antibody molecule

thingiverse

Ever wondered what the antibodies that help protect you from infection look like? This is a model of one type (class) of antibody, called IgG (immunoglobulin G) It's a symmetrical structure consisting of two "heavy" chains, which give the Y shape in the model, and two additional chains, the "light" chains, which are associated with each of the arms of the Y. This model is derived from an x-ray crystallographic structure of IgG1, which is available from the protein databank (PDB). The nominal molecular surface of the IgG has been skinned, so all the various individual molecules get fused into a continuous surface. Unless my quick calculation is off, the model, if left as is, is approximately 6.2 million times bigger than an actual IgG. The two identical arms (each being partly made of a heavy chain and a light chain, bind to the antibodies target "antigen" - so a single IgG can bind to two identical target molecules. Search for antibody on the web, if you are curious about the detail! I recently made a gold (painted) antibody as a gift for someone leaving my unit, comes out quite nice! How I Designed This Molecular visualization software I used a file from the protein databank (PDB) and used an open-source molecule visualizer called Chimera to apply a molecular surface to the molecule. I turned off all other viewing options ( ribbons, atoms etc) Instructions Needs complete support, get it as flat as possible to the build surface, so have a good look before generating the code. I'll try making it as two colour next time, so heavy and light chains show themselves.