RAF kinase

thingiverse

This is one part of dimer of RAF protein kinase, and with its whole structure, it contains a dimer of the RAF kinase domain in the center and two copies of MEK bound on the outside. As we know, RAF has important roles in cell metabolism and if it does have mutations in one nucleotide in the gene, it will cause dramatic consequences. Therefore, I want to show people what is like. And if you want to check the information of this molecular, you can go to website with url:http://pdb101.rcsb.org/motm/195. And moreover, if you want to find this stl file to do some modification, you can download file from RCSB(http://www.rcsb.org/pdb/explore/explore.do?structureId=4mne) Print Settings Printer Brand: MakerBot Printer: MakerBot Replicator (5th Generation) Rafts: No Supports: Yes Notes: This molecular is also be designed in VMD software and tinkered in Tinkercad. When you transform stl file into Tinkercad, you should be aware of its scale, which needs to be 90-95%. The supports I used are 3.5mm in diameter. What you should be aware of is that the minimal diameter for supports is 3.0mm. If you are afraid of having some flaws when printed. you can add some more supports and rafts. By the way, higher supports need to be strengthened. When I first got this molecular done, I was pretty happy to see it in that it was beautiful to some extent and had a little flaws. The supports are pretty strong mostly, but it still had some problems in supports and you can see from the pictures I had uploaded. Therefore, I made some modifications to it and it will strengthen my supports. Post-Printing From pictures I posted, you can see that I have not finished my trimming and modifying in that I have no knife in my hand and I need to do it with my bare hands. Therefore, if you can it by yourself, you should better use knife to do this. lol!